Some valid points have been made so far. I would add that you should work to a minimum output. I would suggest you base it on:
Maximum demand from the dialysis machine x number of machines x 1.25
So for 10 machines I would be looking at a minimum output of 16 L/min. If there is likely to be further expansion in the near future, it will be worth factoring that in.
The other point not discussed is the quality of water you want. Are you looking at AAMI or higher quality? Also are you looking to have a back-up system? Both of these aspects will make a sizeable difference in cost.