Mark, are the users having problems with loss of delivery 0.1ml/hr, at startup, or is the pump delivery fluctuating excessively at this low rate and causing unwanted physiological effects - is it just that problems in maintaining the patient's condition are being observed at these rates and everything is Ok at higher delivery rates? Hence the reason you're suggesting higher delivery rates and dilution of the drug. It's just that I don't fully understand what John is getting at and I'd like to, if possible.
